Basic Molecular Information

Basic Information

DICL ID
DICL_CP_0331757
PubChem CID
N/A (Not available)
Molecular Formula
C18H24N4O
Molecular Weight
312.417 g/mol
Synonyms/Alias
N/A (Not available)
InChI Key
JJPQZVQWGJQPTR-UHFFFAOYSA-N
InChI
InChI=1S/C18H24N4O/c1-13-8-9-15(12-19-13)11-18(23)20-17-10-14(2)21-22(17)16-6-4-3-5-7-16/h8-10,12,16...
IUPAC Name
N-(1-cyclohexyl-3-methyl-1H-pyrazol-5-yl)-2-(6-methylpyridin-3-yl)acetamide
CAS Number
N/A (Not available)

Structure Information

Chemical Structure Visualization

SMILES Notation
2D Molecular Drawing
Carbon (C)
Hydrogen (H)
Oxygen (O)
Nitrogen (N)
Sulfur (S)
SDF

47 49 0 0 0 0 0 0 0 0999 V2000
5.7023 1.6072 1.6864 C 0 0 0 0 0 0 0 0 0 0 0 0
4.9005 1.0173 0.5706 C 0 0 0 0 0 0 0 0 0 0 0 0
3.9192 1.751...

Experimental Data

Activity Data

Target Ion Channel
G protein activated inward rectifier potassium channel 1/2
Uniprot Accession Number
Function
Activator
Species
Rattus norvegicus (Rat)
IC50
IC50: 3900 nM
EC50
N/A (Not available)
Ki
N/A (Not available)
Kd
N/A (Not available)
Inhibition
N/A (Not available)

Experimental Conditions

pH
pH 7.2
Holding Potential
Not specified
Temperature
37 °C
Test Method
Flux assay (Thallium ion)
Test Species
Not specified

Binding Information

Binding Site
Not specified
Binding Site Residue
Not specified

Disease Information

Related Disease
Not specified

References

URL
N/A (Not available)
PMID
Patent
N/A (Not available)

Computed Properties

Heavy Atom Count
23
Rotatable Bonds
4
logP
3.5813
Complexity
90.3937
TPSA (Ų)
59.81
H-Bond Donors
1
H-Bond Acceptors
4
Ring Count
3
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